Tecentriq 1200mg Injection (Atezolizumab) – Complete Product Description

Tecentriq 1200mg Injection (Atezolizumab) is a prescription oncology medicine manufactured by Roche and used as an immunotherapy treatment for selected types of cancer. It contains atezolizumab, a humanized monoclonal antibody that works by blocking the PD-L1 (programmed death-ligand 1) immune checkpoint pathway.

Tecentriq 1200mg/20mL is supplied as a concentrated solution for intravenous infusion. Each single-use vial contains 1200mg of atezolizumab in 20mL, equivalent to 60mg/mL. The pack size for this product is 1 injection/vial.

Atezolizumab helps the immune system recognize and respond to certain cancer cells by preventing PD-L1 from suppressing immune activity. Depending on the cancer type and patient’s clinical characteristics, Tecentriq may be prescribed alone or alongside other anticancer treatments.

Tecentriq 1200mg Injection – Product Information

Brand Name: Tecentriq
Active Ingredient: Atezolizumab
Strength: 1200mg
Concentration: 1200mg/20mL (60mg/mL)
Dosage Form: Concentrate for solution for infusion
Route of Administration: Intravenous (IV) infusion
Manufacturer: Roche
Pack Size: 1 injection/vial
Drug Class: PD-L1 immune checkpoint inhibitor
Therapeutic Class: Antineoplastic / Immunotherapy
Prescription Status: Prescription medicine

Tecentriq 1200mg is supplied as a single-use, preservative-free vial containing a clear, colourless to slightly yellow solution. It is intended to be diluted and administered through intravenous infusion by an appropriately trained healthcare professional.

What Is Tecentriq 1200mg Injection Used For?

Tecentriq (Atezolizumab) is used for specific cancer indications according to approved prescribing information. Roche’s Pakistan information lists Tecentriq among treatments for selected forms of non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), hepatocellular carcinoma (HCC), and BRAF V600 mutation-positive unresectable or metastatic melanoma, depending on the patient’s condition and treatment setting.

Tecentriq for Non-Small Cell Lung Cancer

Atezolizumab may be prescribed for selected patients with non-small cell lung cancer (NSCLC). Its use can depend on factors such as disease stage, PD-L1 expression, previous treatments and relevant molecular characteristics.

Tecentriq can be used in certain treatment settings as monotherapy or as part of a combination regimen, according to the approved indication.

Tecentriq for Small Cell Lung Cancer

Tecentriq may be used as part of treatment for selected patients with extensive-stage small cell lung cancer (ES-SCLC). In appropriate patients, atezolizumab can be combined with chemotherapy as part of an oncology treatment plan.

Tecentriq for Hepatocellular Carcinoma

Tecentriq is also used for selected patients with unresectable or metastatic hepatocellular carcinoma (HCC). Depending on the approved treatment regimen, atezolizumab may be administered in combination with other anticancer medicines.

Tecentriq for Melanoma

Atezolizumab has an approved role in specific patients with BRAF V600 mutation-positive unresectable or metastatic melanoma, where it may be used with appropriate targeted therapy and according to the applicable treatment indication.

How Does Tecentriq (Atezolizumab) Work?

Tecentriq is an immune checkpoint inhibitor. Its active ingredient, atezolizumab, binds to PD-L1, a protein that can be present on cancer cells and immune cells within the tumour environment.

Normally, interaction between PD-L1 and receptors such as PD-1 and B7.1 can reduce immune-cell activity. By blocking PD-L1, atezolizumab can help prevent this immune suppression and allow the body’s immune system to mount a stronger response against cancer cells.

Unlike conventional chemotherapy, Tecentriq works by modifying an immune checkpoint pathway rather than directly destroying rapidly dividing cells.

Tecentriq 1200mg Dose and Administration

Tecentriq 1200mg is administered by intravenous infusion. It must be diluted and given by a healthcare professional experienced in administering oncology medicines.

The exact dosage schedule depends on the cancer being treated, the approved indication, the patient’s clinical condition and whether Tecentriq is being administered alone or with other medicines.

For some approved indications, the 1200mg regimen is administered at intervals of approximately every three weeks, while other Tecentriq dosing schedules may apply depending on the indication.

Patients should not attempt to inject or administer Tecentriq themselves. The treating oncologist should determine the appropriate dose, infusion schedule and duration of treatment.

Common Side Effects of Tecentriq 1200mg

Like all prescription medicines, Tecentriq can cause side effects. Because atezolizumab affects immune-system activity, some adverse reactions are related to excessive or abnormal immune activation.

Possible side effects include:

• Fatigue
• Decreased appetite
• Nausea
• Diarrhea
• Constipation
• Cough
• Shortness of breath
• Fever
• Rash
• Itching
• Joint pain
• Muscle pain
• Weakness
• Infusion-related reactions

Patients receiving Tecentriq should be monitored for potentially serious immune-mediated reactions.

Serious Immune-Related Side Effects

Atezolizumab can cause inflammation in different organs. Serious reactions may involve the:

• Lungs
• Liver
• Intestines
• Kidneys
• Thyroid and other endocrine glands
• Skin
• Nervous system
• Heart
• Muscles

Patients should promptly inform their healthcare provider if they develop new or worsening breathing problems, persistent cough, severe diarrhea, abdominal pain, yellowing of the skin or eyes, significant rash, severe weakness, unusual headaches or other concerning symptoms.

Early recognition and appropriate management of immune-mediated adverse reactions are important during Tecentriq treatment.

Precautions Before Using Tecentriq

Before receiving Tecentriq 1200mg Injection, inform your doctor about your complete medical history and all medicines you are taking.

Special care may be required if you have:

• A history of autoimmune disease
• Lung or breathing problems
• Liver disease
• Kidney problems
• Gastrointestinal disorders
• Hormonal or endocrine disorders
• A history of organ transplantation
• Previous treatment with immune checkpoint inhibitors
• Previous severe reactions to monoclonal antibody medicines

Your healthcare professional should also know about any prescription medicines, over-the-counter medicines, supplements or other cancer treatments you are receiving.

Pregnancy and Breastfeeding

Tecentriq may cause harm to a developing fetus because of its mechanism of action. Women who are pregnant or planning to become pregnant should discuss the potential risks with their healthcare provider before treatment.

Patients who could become pregnant should follow their healthcare professional’s recommendations regarding contraception during treatment.

Breastfeeding should also be discussed with the treating physician before receiving Tecentriq.

Tecentriq 1200mg Storage

Tecentriq is a biological medicine that requires appropriate storage and handling.

The vial should be stored according to the manufacturer’s specified conditions and protected from inappropriate temperatures and light. It should not be frozen.

Because Tecentriq is an injectable oncology medicine, storage, preparation and administration should be handled by qualified healthcare professionals or authorized pharmaceutical personnel.

Tecentriq 1200mg Injection Price in Pakistan

The Tecentriq 1200mg Injection price in Pakistan may vary depending on availability, supplier, import costs, exchange rates and current market conditions.

For the latest Tecentriq 1200mg price in Pakistan, customers can contact MedicineWalyDost.com to check current availability and pricing.

Why Choose Tecentriq 1200mg Injection?

Tecentriq contains atezolizumab, an established PD-L1 immune checkpoint inhibitor developed by Roche. Its targeted mechanism provides an important immunotherapy option for appropriately selected patients with certain cancers.

The 1200mg/20mL presentation provides a convenient single-use vial for intravenous infusion under professional medical supervision.

Tecentriq is a specialized cancer medicine and should only be used when prescribed by an oncologist who has evaluated the patient’s diagnosis, cancer stage, biomarkers, previous treatment and overall health.

Frequently Asked Questions About Tecentriq 1200mg

What is Tecentriq 1200mg Injection?

Tecentriq 1200mg Injection is an intravenous immunotherapy medicine containing atezolizumab. It is a PD-L1 immune checkpoint inhibitor used for selected cancer indications.

What is the generic name of Tecentriq?

The generic name is atezolizumab.

Who manufactures Tecentriq 1200mg?

Tecentriq is manufactured by Roche. Roche’s Pakistan product information lists Tecentriq 840mg and 1200mg IV presentations.

What is the pack size of Tecentriq 1200mg?

The product supplied for this listing has a pack size of 1 injection/vial. The 1200mg presentation contains 1200mg of atezolizumab in 20mL.

How is Tecentriq 1200mg administered?

Tecentriq 1200mg is administered by intravenous infusion after dilution. It should only be prepared and administered by an appropriately trained healthcare professional.

Is Tecentriq chemotherapy?

No. Tecentriq is classified as immunotherapy, specifically a PD-L1 immune checkpoint inhibitor. It may, however, be used together with chemotherapy or other anticancer medicines for certain indications.

What cancers can Tecentriq treat?

Depending on the approved indication and patient characteristics, Tecentriq may be used for selected forms of NSCLC, SCLC, HCC and BRAF V600 mutation-positive unresectable or metastatic melanoma, among other jurisdiction-specific indications.

Can Tecentriq be purchased without a prescription?

Tecentriq is a specialized prescription oncology medicine and should only be used under the supervision of a qualified oncologist or healthcare professional.

Order Tecentriq 1200mg Injection in Pakistan

Looking for Tecentriq 1200mg Injection (Atezolizumab) in Pakistan? MedicineWalyDost.com can help customers check availability and current pricing for this specialized oncology medicine.

Before placing an order, verify the brand, strength, active ingredient, manufacturer, pack size and prescription requirements with your healthcare provider or pharmacist.

Order Tecentriq 1200mg Injection from MedicineWalyDost.com and contact us for current availability and pricing.

Important Medical Disclaimer

Tecentriq 1200mg Injection is a prescription cancer medicine. This product information is intended for educational and e-commerce purposes only and should not replace the advice, diagnosis or treatment plan provided by a qualified oncologist or healthcare professional. Do not use, stop or change the dose of Tecentriq without medical advice.