Tenofo-B Tablet 300mg: Uses, Side Effects, and Price in Pakistan

Tenofo-B Tablet 300mg is an antiviral medication used for the treatment of HIV (Human Immunodeficiency Virus) infection and chronic Hepatitis B Virus (HBV) infection. It contains Tenofovir Disoproxil Fumarate, a nucleotide reverse transcriptase inhibitor (NRTI) that blocks viral replication, thereby reducing viral load and preventing disease progression.

Manufactured by Getz Pharma, Tenofo-B is an essential part of antiretroviral therapy (ART) for HIV and a first-line treatment for chronic Hepatitis B in adults. Regular use helps manage symptoms, prevent complications, and improve overall quality of life.

How Tenofo-B Tablet 300mg Works

The active ingredient, Tenofovir Disoproxil Fumarate (300mg), is a prodrug that converts into tenofovir in the body. It works by inhibiting:

• Reverse transcriptase enzyme in HIV, preventing the virus from converting RNA into DNA and stopping its replication.
• HBV polymerase enzyme in Hepatitis B, which blocks the virus from multiplying and damaging the liver.

By stopping the virus from reproducing, Tenofo-B lowers viral load, protects the immune system, and reduces liver damage.

Indications and Uses

HIV Infection

• Used in combination with other antiretroviral drugs to suppress HIV and maintain immune function.
• Helps prevent the progression to AIDS (Acquired Immunodeficiency Syndrome) and reduces the risk of opportunistic infections.

Chronic Hepatitis B

• Indicated for patients with active viral replication, elevated liver enzymes (ALT/AST), and histological signs of liver inflammation or fibrosis.
• Helps prevent complications such as liver cirrhosis and hepatocellular carcinoma (liver cancer).

Dosage and Administration

• For HIV Treatment: One tablet (300mg) once daily in combination with other antiretroviral medications.
• For Chronic Hepatitis B: One tablet (300mg) once daily as a monotherapy.

How to Take:

• Can be taken with or without food.
• Must be taken at the same time every day to maintain drug effectiveness.
• Do not skip doses or discontinue use without medical advice, as this can lead to viral resistance.

If a dose is missed, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue the regular schedule.

Side Effects of Tenofo-B Tablet

Most people tolerate Tenofo-B well, but some mild to moderate side effects may occur, including:

• Nausea and vomiting
• Diarrhea
• Dizziness and headache
• Fatigue and weakness

In rare cases, serious side effects may occur, such as:

• Lactic acidosis (symptoms: muscle pain, trouble breathing, rapid heartbeat, dizziness)
• Liver toxicity (symptoms: jaundice, dark urine, abdominal pain, nausea)
• Kidney problems, including kidney failure
• Bone density loss, leading to osteoporosis

If any severe symptoms occur, seek medical attention immediately.

Precautions and Warnings

• Liver and Kidney Function: Regular monitoring of liver enzymes and kidney function is recommended.
• Hepatic Flares: Stopping Tenofo-B suddenly can cause a severe flare-up of Hepatitis B.
• Bone Health: Long-term use may cause bone mineral density loss, increasing the risk of fractures.
• Pregnancy & Breastfeeding: Safe for pregnant women under medical supervision. Breastfeeding mothers should consult a doctor before use.
• Dietary Considerations: Avoid excessive alcohol and fatty foods, as they can worsen liver function. Staying hydrated is crucial to protect kidney health.

Tenofo-B Tablet Price in Pakistan

The price of Tenofo-B Tablet 300mg in Pakistan may vary depending on the pharmacy and location. It is recommended to check with local medical stores or online pharmacies for the latest pricing.

Frequently Asked Questions (FAQs)

What is the price of Tenofo-B Tablet 300mg in Pakistan?

The price varies by region and pharmacy. Check with local and online pharmacies for the latest rates.

How should I take Tenofo-B Tablet 300mg?

Take one tablet daily with or without food. Maintain a consistent dosing schedule and do not skip doses.

What are the common side effects of Tenofo-B Tablet 300mg?

Common side effects include nausea, diarrhea, dizziness, headache, and fatigue. Serious side effects like kidney damage or lactic acidosis are rare but require medical attention.

Can Tenofo-B Tablet 300mg be used during pregnancy?

Yes, it can be used under medical supervision. Pregnant women should consult their doctor before starting treatment.

Are there any dietary restrictions while taking Tenofo-B Tablet 300mg?

Avoid alcohol and high-fat diets, as they can impact liver function. Stay hydrated to support kidney health.

Conclusion

Tenofo-B Tablet 300mg is a highly effective antiviral medication for HIV and Hepatitis B treatment. It reduces viral load, improves immune function, and prevents long-term complications like liver failure and AIDS. To ensure maximum benefits, take it consistently, monitor your health, and follow medical advice.

For accurate pricing and availability, consult local or online pharmacies in Pakistan.

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