Palboxen 125 mg Capsule (Palbociclib) – Complete Product Overview

Palboxen 125 mg Capsule contains Palbociclib, a targeted, oral CDK4/6 inhibitor used to treat certain types of hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer. It works by blocking key proteins essential for cancer cell division, slowing tumor growth, and extending progression-free survival.

Key Benefits & Therapeutic Applications

• Approved for use in HR+ / HER2– advanced breast cancer, in combination with aromatase inhibitors (like letrozole) or fulvestrant.

• Offers the benefit of oral administration, enabling effective home-based oncology care and reducing clinic visits.

• Proven to delay disease progression and improve outcomes when used under expert oncologist supervision.

• Often incorporated in first-line therapy for select patients or used after disease progression on prior endocrine therapy.

Manufacturer & Pack Size in Pakistan

• Brand Name: Palboxen 125 mg Capsule

• Generic Name: Palbociclib (oral)

• Manufacturer: Everest Pharmaceuticals Ltd. Produced by a reputable oncology-focused pharmaceutical company licensed in Pakistan.

• Pack Size Options:

  • 21 capsules per pack (intended for 3-week-on, 1-week-off dosing cycle)

  • 42 capsules pack (for two cycles)

Always ensure you order the correct pack size as prescribed by your oncologist.

Dosage and Administration

• Typical regimen: 125 mg orally once daily for 21 consecutive days, followed by a 7-day break — making each 28-day cycle.

• Taken with food, usually in the morning, at the same time each day.

• Always swallow the capsule whole — do not open, crush, or mix with food.

• Dose reductions (to 100 mg or 75 mg daily) are common for patients experiencing neutropenia or other adverse effects and are guided by regular blood count monitoring.

Side Effects of Palboxen 125mg Capsules

Common Side Effects:

• Neutropenia (low white blood cells)

• Anemia (low hemoglobin)

• Fatigue, nausea

• Stomatitis (mouth sores)

• Diarrhea or constipation

• Hair thinning

• Increased risk of infections

Serious Adverse Effects:

• Severe neutropenia leading to febrile neutropenia

• Pulmonary embolism or deep vein thrombosis (rare)

• Severe lung inflammation (interstitial lung disease)

• Liver dysfunction

Regular complete blood counts (CBCs) and liver tests are essential throughout treatment. Most side effects can be managed—especially if caught early and handled with dose modifications.

Important Precautions

• Complete blood count monitoring before starting each cycle.

• Monitor liver function and kidney health throughout treatment.

• Stay alert for signs of infection, especially fever during low neutrophil periods.

• Report any respiratory symptoms, especially shortness of breath or persistent cough.

• Avoid grapefruit and grapefruit juice, which can interfere with drug metabolism.

• Avoid live vaccines while on treatment.

Contraindications

• History of hypersensitivity to Palbociclib or formulation components.

• Pregnant or breastfeeding women—do not use; Palboxen is potentially teratogenic.

• Uncontrolled severe infections or hemodynamic instability.

• Patients with severe liver impairment should use under special care or avoid (depending on evaluation).

Always discuss your full medical history and current medications with your oncologist before starting Palboxen.

Palboxen 125mg Price in Pakistan

Ordering from MedicineWalyDost.com, Pakistan’s trusted, leading online pharmacy for oncology and imported medicines, ensures best-value pricing, genuine products, and hassle-free service.

To get the latest price for Palboxen 125 mg Capsules:

• WhatsApp us at +92 315 7733383 for an instant quote and availability.

• Visit MedicineWalyDost.com for product details and to place your order.

Delivery is available across Karachi, Lahore, Islamabad, and all major cities of Pakistan.

Storage Guidelines

• Store at room temperature (20–25 °C), tightly in original packaging.

• Protect from moisture and heat.

• Keep out of reach of children and pets.

• Never use expired capsules.

Frequently Asked Questions (FAQs)

1. How long will I need to take Palboxen?

Treatment continues until disease progression or unacceptable side effects. Many patients stay on therapy for several months to over a year, monitoring efficacy through routine imaging and tumor markers.

2. Can I take Palboxen without an aromatase inhibitor?

No. Palbociclib is intended for use in combination with hormone therapy, typically letrozole or fulvestrant, as prescribed by your oncologist.

3. If I miss a dose, what should I do?

Take it as soon as remembered unless it’s nearly time for your next dose. Do not double up. Inform your oncologist about any missed doses.

4. Is Palboxen covered by insurance in Pakistan?

Coverage depends on your plan. MedicineWalyDost.com can assist with pricing comparisons and guidance on acquiring assistance programs.

5. Can this medicine cure my cancer?

Palboxen is not a cure but can significantly slow disease progression, reduce symptoms, and provide meaningful survival benefits in HR+ / HER2– breast cancer.

Why Buy Palboxen 125mg from MedicineWalyDost.com?

• Authentic, imported oncology-grade medications

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• Expert customer support via WhatsApp: +92 315 7733383

• Nationwide delivery, with priority handling for cancer therapies

• Guaranteed product authenticity—no substitutions, only trusted sourcing

Order Palboxen 125mg Capsules Now

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Your care matters—choose value, trust, and quality for your treatment with Palboxen.