Kisqali (Ribociclib) 200mg Tablet – Product Description

Kisqali (Ribociclib) 200mg Tablet is an advanced cancer medicine manufactured by Novartis. It is mainly used for the treatment of hormone receptor–positive (HR+), HER2-negative breast cancer, either in early-stage cases with high recurrence risk or in advanced/metastatic stages.

Pack Size

One Pack of Kiaqali Tablet contains 63 film-coated Tablets.

Uses and Indications

• Kisqali is prescribed in combination with aromatase inhibitors or fulvestrant for the treatment of HR+, HER2-negative breast cancer.

• It helps reduce the risk of recurrence in early breast cancer and improves survival in advanced or metastatic cases.

• Recommended as part of endocrine-based therapy for better outcomes.

Mechanism of Action

Kisqali belongs to the class of CDK 4/6 inhibitors. It works by blocking enzymes (cyclin-dependent kinases) that promote cancer cell growth. By slowing down or stopping tumor cell division, it controls disease progression while preserving more healthy cells compared to chemotherapy.

Dosage and Administration

• Each film-coated tablet contains 200mg of Ribociclib.

• The standard dose is 600mg daily (three tablets) for 21 consecutive days, followed by a 7-day rest period, completing a 28-day cycle.

• Doses may be adjusted depending on liver or kidney function and patient tolerance.

• Tablets should be swallowed whole with or without food, at the same time each day.

Key Benefits

• Targeted therapy approach with fewer effects on healthy cells.

• Reduces recurrence risk in early breast cancer.

• Improves progression-free survival and overall survival in advanced breast cancer patients.

• Backed by strong clinical trial results in the MONALEESA studies.

Side Effects

Common side effects of Kisqali 200mg Tablet include:

• Low white blood cell count (neutropenia)

• Fatigue and weakness

• Nausea, vomiting, or diarrhea

• Hair loss (alopecia)

• Increased liver enzymes

• Headache, cough, or rash

Serious side effects may include heart rhythm problems (QT prolongation), lung inflammation, or liver toxicity. Always report unusual symptoms to your doctor.

Drug Interactions

• Kisqali is metabolized by CYP3A4 enzymes. Avoid grapefruit and strong CYP3A4 inhibitors or inducers.

• May interact with other medicines, so inform your doctor about all drugs and supplements you use.

Storage

• Store Kisqali tablets in their original pack, away from moisture and heat.

• Keep out of reach of children.

Kisqali (Ribociclib) 200mg Tablet Price in Pakistan

The price of Kisqali 200mg Tablet in Pakistan may vary depending on stock availability and importer. To get the best price and quick delivery, order directly from MedicineWalyDost.com.

FAQs – Kisqali Ribociclib 200mg

Q: What is Kisqali used for?
A: Kisqali is used for the treatment of HR-positive, HER2-negative breast cancer in both early and advanced stages.

Q: Does Kisqali cause hair loss?
A: Yes, hair thinning or hair loss may occur in some patients but is usually temporary.

Q: How long should Kisqali be taken?
A: Kisqali is usually taken in treatment cycles and continued as long as it is effective and tolerated.

Q: Who manufactures Kisqali?
A: Kisqali is manufactured by Novartis.