Entyvio 300mg Injection (Vedolizumab) – Imported

Entyvio 300mg Injection contains Vedolizumab, a biologic medicine used to treat certain chronic inflammatory bowel diseases. It is a targeted monoclonal antibody that works primarily in the gastrointestinal tract by reducing the movement of specific inflammatory cells into the intestinal tissue.

Entyvio is used for eligible patients with moderately to severely active ulcerative colitis and Crohn’s disease when conventional treatments or other therapies have not provided an adequate response or are not appropriate.

Uses of Entyvio 300mg Injection

Entyvio may be prescribed for adults with:

• Moderately to severely active ulcerative colitis
• Moderately to severely active Crohn’s disease

The medicine may be used when patients have had an inadequate response, lost response, or were unable to tolerate other approved treatments, depending on the applicable treatment guidelines and product labeling.

How Entyvio Works

Vedolizumab is a gut-selective integrin receptor antagonist. It specifically binds to the α4β7 integrin on certain white blood cells.

By blocking the interaction between α4β7 integrin and MAdCAM-1, Vedolizumab reduces the migration of these inflammatory cells into the gastrointestinal tract. This helps decrease intestinal inflammation and can improve symptoms associated with inflammatory bowel disease.

Administration and Dosage

Entyvio 300mg Injection is administered by intravenous infusion by a qualified healthcare professional.

The usual adult treatment schedule involves an initial dose followed by additional doses at specific intervals. Maintenance treatment is then continued according to the prescribing physician’s assessment and the patient’s response.

The exact treatment schedule can vary depending on the formulation, indication, clinical response, and local prescribing information. Entyvio should only be prepared and administered according to the approved product instructions.

Possible Side Effects

Some patients receiving Entyvio may experience side effects such as:

• Headache
• Nausea
• Joint pain
• Nasopharyngitis
• Upper respiratory tract infections
• Fatigue
• Cough
• Fever
• Infusion-related reactions
• Abdominal discomfort

Serious infections and hypersensitivity reactions can occur. Patients should promptly report unusual or severe symptoms to their healthcare provider.

Important Precautions

Before starting Entyvio treatment, patients should inform their doctor about their complete medical history and all medicines they are taking.

Particular attention may be required for patients with:

• Active or recurrent infections
• A history of tuberculosis or exposure to tuberculosis
• Severe allergic reactions to previous biologic medicines
• Liver problems
• Conditions requiring immunosuppressive medicines

Patients may require screening for certain infections before treatment. Live vaccines may require special consideration during treatment.

Pregnancy and Breastfeeding

Patients who are pregnant, planning pregnancy, or breastfeeding should discuss Entyvio treatment with their healthcare professional. The physician can assess the potential benefits and risks according to the patient’s individual circumstances.

Storage

Entyvio 300mg Injection generally requires refrigerated storage at 2°C to 8°C. The product should be protected from light and should not be frozen or shaken. Appropriate cold-chain handling is important to preserve the quality of this biologic medicine.

Always follow the storage requirements provided with the specific imported product.

Product Information

• Product Name: Entyvio 300mg Injection
• Active Ingredient: Vedolizumab
• Strength: 300mg
• Dosage Form: Powder for concentrate for solution for infusion
• Route: Intravenous infusion
• Pack Size: 1 vial
• Manufacturer/Brand: Entyvio
• Origin: Imported

Why Choose Entyvio 300mg Injection?

Entyvio contains Vedolizumab, a targeted biologic therapy specifically designed to reduce inflammatory cell trafficking into the gastrointestinal tract. Its gut-selective mechanism makes it an established treatment option for eligible patients with moderate-to-severe ulcerative colitis or Crohn’s disease.

For imported biologic medicines, proper storage and cold-chain transportation are particularly important. Entyvio should be obtained from a reliable pharmaceutical supplier and used only under the supervision of a qualified healthcare professional.

Frequently Asked Questions

What is Entyvio 300mg Injection used for?

Entyvio is used to treat moderately to severely active ulcerative colitis and Crohn’s disease in eligible patients.

What is the generic name of Entyvio?

The active ingredient in Entyvio is Vedolizumab.

How is Entyvio administered?

Entyvio 300mg is administered through intravenous infusion by a trained healthcare professional.

Is Entyvio a steroid?

No. Entyvio is a biologic monoclonal antibody and is not a corticosteroid.

Does Entyvio require refrigeration?

Yes. Entyvio generally needs to be stored at 2°C to 8°C and protected from light.

Can Entyvio be self-administered?

The intravenous formulation is administered by a healthcare professional. Patients should not attempt to prepare or administer the IV formulation themselves.

How long does Entyvio treatment continue?

Treatment duration depends on the patient’s condition, response to therapy, and the treating specialist’s assessment. Long-term maintenance treatment may be required for inflammatory bowel disease.