Diflucan 150mg Capsule contains fluconazole, an antifungal medication used to treat various fungal and yeast infections. It is particularly effective against infections caused by Candida species. The 150mg dosage is commonly prescribed as a single-dose treatment for vaginal candidiasis (vaginal yeast infections).

Uses:

Vaginal candidiasis: A single 150mg oral dose is typically effective.

Oral thrush (oropharyngeal candidiasis): Dosage varies based on severity and patient response.

Esophageal candidiasis: Treatment duration and dosage depend on infection severity.

Systemic Candida infections: Dosage and duration are determined by the infection’s location and severity.

Cryptococcal meningitis: Used in both treatment and maintenance therapy.

Prophylaxis: Prevents fungal infections in immunocompromised individuals, such as those undergoing chemotherapy or organ transplantation.

Mechanism of Action: Fluconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately causes fungal cell death.

Dosage and Administration:

Vaginal candidiasis: One 150mg capsule taken orally as a single dose.

Other infections: Dosage varies; always follow your healthcare provider’s instructions.

Can be taken with or without food.

Ensure the full course is completed, even if symptoms improve earlier.

Common Side Effects:

Headache

Nausea

Abdominal pain

Diarrhea

Dizziness

Changes in taste

Serious Side Effects:

Liver toxicity: Symptoms include jaundice, dark urine, and persistent nausea.

Severe skin reactions: Such as Stevens-Johnson syndrome.

QT prolongation: A heart rhythm condition that can be serious.

Allergic reactions: Rash, itching, swelling, severe dizziness, or trouble breathing.

Precautions:

Pregnancy: Use only if clearly needed; consult your doctor.

Breastfeeding: Fluconazole passes into breast milk; discuss risks with your healthcare provider.

Liver disease: Use with caution; liver function should be monitored.

Heart conditions: Inform your doctor of any heart rhythm disorders.

Drug interactions: Inform your healthcare provider about all medications you’re taking, as fluconazole can interact with several drugs.

Storage:

Store at room temperature away from moisture and heat.

Keep out of reach of children.

Manufacturer:

Brand Name: Diflucan

Manufacturer: Pfizer

Packaging: Available as a single 150mg capsule.