Azarest 300mg Tablet (Azacitidine) – Complete Product Description & Order in Pakistan

What is Azarest 300mg Tablet?

Azarest 300mg Tablet is an oral chemotherapy medicine containing Azacitidine, used in the treatment of myelodysplastic syndromes (MDS) and certain types of acute myeloid leukemia (AML). This oral Azacitidine formulation is designed for daily dosing over treatment cycles, offering a more convenient alternative to traditional injectable forms.

Azarest 300mg belongs to a class of hypomethylating agents that work by altering abnormal DNA methylation in cancer cells, helping the bone marrow produce healthy blood cells and suppressing the growth of abnormal cells.

Medical Uses of Azarest 300mg in Pakistan

Azarest 300mg is prescribed by oncologists and hematologists across Pakistan for:

• Higher-risk Myelodysplastic Syndromes (MDS)

• Chronic Myelomonocytic Leukemia (CMML)

• Acute Myeloid Leukemia (AML) in patients unfit for intensive chemotherapy

• Post-transplant relapse prevention (in select protocols)

By restoring healthy cell growth, Azarest helps reduce transfusion needs and controls disease progression in bone marrow-related cancers.

How Azarest 300mg Tablets Work

Azacitidine in Azarest inhibits DNA methyltransferase, reactivating tumor-suppressing genes. It promotes normal differentiation of blood cells and slows down abnormal cancer cell multiplication.

This oral therapy provides patients with the flexibility of home-based cancer care, reducing hospital visits compared to injectable chemotherapy.

Dosage & Administration (Tablet Form)

• Standard dose: Typically 300mg once daily for 14 consecutive days in a 28-day cycle.

• Dosage may vary based on patient’s body surface area, renal function, blood counts, and response to therapy.

• Should be taken with or without food, at the same time each day.

• Swallow the tablet whole with water. Do not crush or split the tablet.

Always follow your oncologist’s exact instructions. Dosage may be adjusted based on side effects or treatment response.

Manufacturer & Packaging Information

• Brand Name: Azarest 300mg Tablet

• Generic Name: Azacitidine (Oral)

• Manufactured by: Everest Pharmaceuticals Ltd. – A reputable pharmaceutical company with specialization in oncology treatment.

• Form: Oral tablets

• Pack Size: Available in packs of 14 tablets

Side Effects of Azarest 300mg Tablet

Common Side Effects:

• Nausea, vomiting

• Diarrhea or constipation

• Decreased appetite

• Fatigue or weakness

• Low white blood cell counts (increased infection risk)

• Low platelet counts (bruising, bleeding)

• Anemia (shortness of breath, pale skin)

Serious Side Effects:

• Febrile neutropenia (fever with low white cells)

• Severe gastrointestinal symptoms

• Kidney or liver function abnormalities

• Secondary infections

Regular monitoring of complete blood counts and organ function is essential during treatment with Azarest tablets.

Precautions Before Taking Azarest

• Pregnancy & Breastfeeding: Azarest is not safe during pregnancy and may harm the unborn baby. Avoid breastfeeding while on treatment.

• Fertility: May affect reproductive health; discuss fertility preservation with your doctor.

• Renal or hepatic impairment: Requires dosage adjustment or careful monitoring.

• Drug interactions: Inform your doctor of all medicines, especially blood thinners or immunosuppressants.

Do not consume alcohol, and avoid live vaccines during treatment.

Contraindications

Do not take Azarest 300mg Tablet if:

• You are allergic to Azacitidine or any excipients

• You have uncontrolled infections

• You are pregnant or breastfeeding

• Severe organ dysfunction (without specialist evaluation)

Azarest 300mg Price in Pakistan

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Storage Instructions

• Store Azarest tablets at room temperature (20–25°C).

• Keep tablets in the original packaging, away from light and moisture.

• Keep out of reach of children and pets.

Frequently Asked Questions (FAQs)

1. How long does Azarest treatment last?

Treatment is typically given in 28-day cycles and continues for several months depending on response. Some patients may remain on treatment for 6–12 months or longer.

2. Can Azarest tablets be taken at home?

Yes. One of the key benefits of Azarest is that it allows oral treatment from home, improving convenience for patients.

3. What if I miss a dose?

If a dose is missed, take it as soon as you remember unless it’s close to the next dose. Never double-dose. Inform your doctor if multiple doses are missed.

4. Is Azarest 300mg covered by insurance in Pakistan?

Coverage depends on your insurance provider. However, MedicineWalyDost.com can guide you to affordable access options and provide verified medicines at competitive rates.

5. Can Azarest cure MDS or AML?

Azarest is not a cure, but it can significantly prolong survival, delay progression, and improve quality of life in eligible patients.

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