Avastin 100mg Injection (Bevacizumab) – Complete Product Description

Avastin 100mg Injection (Bevacizumab) is a prescription oncology medicine manufactured by Roche. It contains bevacizumab, a recombinant monoclonal antibody that targets vascular endothelial growth factor (VEGF), an important protein involved in the formation of new blood vessels.

Cancer cells can stimulate the development of new blood vessels through a process called angiogenesis, allowing tumors to receive oxygen and nutrients needed for growth. Bevacizumab binds to VEGF and inhibits its activity, helping reduce the formation of new blood vessels that support tumor growth.

Avastin 100mg is supplied as a concentrate for solution for intravenous infusion and is intended to be administered by a qualified healthcare professional. The product listed here is manufactured by Roche and supplied in a pack size of 1 injection/vial.

Avastin 100mg Injection – Product Information

Brand Name: Avastin
Active Ingredient: Bevacizumab
Strength: 100mg
Dosage Form: Concentrate for solution for intravenous infusion
Route of Administration: Intravenous (IV) infusion
Manufacturer: Roche
Pack Size: 1 injection/vial
Drug Class: Anti-VEGF monoclonal antibody
Therapeutic Class: Antineoplastic / Targeted cancer therapy
Prescription Status: Prescription medicine

Avastin is a specialized biological medicine. It must be prepared, diluted and administered by appropriately trained healthcare professionals.

What Is Avastin 100mg Injection Used For?

Avastin (Bevacizumab) is used as part of specific cancer treatment regimens for selected patients. Depending on the cancer type and applicable approved indication, bevacizumab may be used for:

• Metastatic colorectal cancer
• Non-small cell lung cancer
• Glioblastoma
• Metastatic renal cell carcinoma
• Cervical cancer
• Ovarian cancer
• Fallopian tube cancer
• Primary peritoneal cancer
• Other approved cancer indications in specific treatment settings

The suitability of Avastin depends on the patient’s diagnosis, cancer stage, previous treatments, overall health and the treatment protocol selected by the oncologist.

Avastin for Colorectal Cancer

Bevacizumab may be used with chemotherapy for selected patients with metastatic colorectal cancer.

By blocking VEGF, Avastin helps interfere with the tumor’s ability to develop new blood vessels. It may be incorporated into specific chemotherapy regimens according to the oncologist’s treatment plan.

Avastin for Non-Small Cell Lung Cancer

Avastin may be used with certain chemotherapy regimens in appropriately selected patients with non-squamous non-small cell lung cancer (NSCLC).

The oncologist determines whether bevacizumab is appropriate based on the patient’s cancer characteristics, medical history and treatment goals.

Avastin for Renal Cell Carcinoma

Bevacizumab may be used in combination with other systemic therapy for selected patients with metastatic renal cell carcinoma.

Avastin for Glioblastoma

Avastin may be prescribed for certain patients with glioblastoma, depending on the treatment setting and applicable medical guidelines.

Avastin for Cervical and Other Gynecological Cancers

Bevacizumab may also be used in selected treatment regimens for certain cervical, ovarian, fallopian tube and primary peritoneal cancers.

The exact indication and combination therapy depend on the patient’s condition and the approved treatment protocol.

How Does Avastin (Bevacizumab) Work?

Avastin contains bevacizumab, a monoclonal antibody that specifically binds to VEGF-A.

VEGF is a signaling protein that promotes the growth of new blood vessels. Tumors can release VEGF to stimulate angiogenesis and create a blood supply that supports their continued growth.

By binding to VEGF, bevacizumab reduces VEGF activity and can inhibit the development of new blood vessels within and around the tumor.

This mechanism makes Avastin an anti-angiogenic targeted therapy.

Avastin does not work in the same way as conventional chemotherapy. Instead, it targets a biological pathway that tumors can use to support their growth.

Avastin 100mg Dose and Administration

Avastin 100mg is administered through intravenous infusion after appropriate dilution.

The dose is determined by the treating oncologist based on the:

• Type of cancer
• Treatment regimen
• Patient’s body weight
• Overall health
• Other medicines being administered
• Response to treatment
• Occurrence of adverse effects

Depending on the indication, bevacizumab may be administered at intervals such as every 2 or 3 weeks.

The 100mg vial may be used as part of the patient’s calculated treatment dose. The treating healthcare professional determines the total dose required.

Do not self-administer Avastin 100mg Injection.

Common Side Effects of Avastin 100mg

Like all medicines, Avastin can cause side effects. The severity and frequency can vary between patients.

Commonly reported adverse effects may include:

• High blood pressure
• Fatigue
• Weakness
• Headache
• Nosebleeds
• Diarrhea
• Nausea
• Abdominal discomfort
• Loss of appetite
• Joint pain
• Muscle pain
• Protein in the urine
• Infusion-related reactions

Patients should report persistent or severe side effects to their healthcare provider.

Serious Side Effects of Avastin

Avastin can cause serious adverse reactions that require careful medical monitoring.

High Blood Pressure

Bevacizumab can cause or worsen hypertension. Blood pressure should be monitored regularly during treatment.

Severe hypertension may require medical treatment or temporary interruption of Avastin.

Bleeding

Avastin can increase the risk of bleeding.

Patients should immediately report unusual bleeding, severe nosebleeds, coughing up blood, blood in stools or other significant bleeding symptoms.

Gastrointestinal Perforation

A serious but uncommon complication is gastrointestinal perforation.

Patients should seek urgent medical attention if they develop severe or persistent abdominal pain, fever or other symptoms suggestive of a serious abdominal problem.

Wound-Healing Complications

VEGF plays an important role in tissue repair and blood-vessel formation. Avastin can therefore interfere with wound healing.

Patients should inform their healthcare provider about recent surgery, planned surgery or wounds that are not healing normally.

Blood Clots

Bevacizumab may increase the risk of arterial or venous thromboembolic events.

Seek immediate medical attention for symptoms such as sudden chest pain, difficulty breathing, sudden weakness or other symptoms suggestive of a blood clot.

Kidney Problems

Avastin may cause kidney-related complications, including proteinuria.

Healthcare professionals may monitor urine protein and kidney function during treatment.

Precautions Before Using Avastin 100mg

Before receiving Avastin, inform your doctor if you have:

• High blood pressure
• Heart or cardiovascular disease
• A history of blood clots
• Bleeding disorders
• Recent surgery
• Planned surgery
• Slow-healing wounds
• Gastrointestinal disease
• Kidney problems
• Previous severe reactions to bevacizumab or similar biological medicines

Tell your healthcare provider about all prescription medicines, over-the-counter medicines, supplements and other cancer treatments you are taking.

Avastin and Surgery

Special precautions are required when Avastin is used around the time of surgery.

Because bevacizumab can interfere with wound healing, your healthcare team may recommend withholding treatment before and after major surgery.

The appropriate timing depends on the specific clinical situation and should be determined by the treating oncologist and surgeon.

Do not stop Avastin treatment on your own.

Avastin During Pregnancy

Bevacizumab may cause fetal harm and should not be used during pregnancy unless the potential benefits clearly outweigh the risks under specialist medical supervision.

Women who can become pregnant should discuss effective contraception with their healthcare provider before and during treatment and for the recommended period after the final dose.

Patients who become pregnant while receiving Avastin should contact their healthcare provider promptly.

Avastin and Breastfeeding

Patients should discuss breastfeeding with their healthcare provider before receiving Avastin.

Because bevacizumab is a specialized biological medicine, breastfeeding may need to be avoided during treatment and for an appropriate period after treatment.

The treating physician will provide individualized advice based on the patient’s treatment plan.

Avastin 100mg Storage

Avastin is a temperature-sensitive biological medicine that requires appropriate storage and handling.

The unopened vial should be stored according to the manufacturer’s approved storage conditions and protected from light.

Do not freeze or shake Avastin.

After preparation and dilution, the medicine must be handled according to appropriate pharmaceutical procedures.

Avastin should only be prepared and administered by qualified healthcare professionals or authorized pharmaceutical personnel.

Avastin 100mg Injection Price in Pakistan

The Avastin 100mg Injection price in Pakistan may vary depending on availability, supplier, import costs, exchange rates and prevailing market conditions.

For the latest Avastin 100mg price in Pakistan, customers can contact MedicineWalyDost.com to check current availability and pricing.

Specialized oncology medicine prices can change, so customers should confirm the latest price before placing an order.

Why Choose Avastin 100mg Injection?

Avastin contains bevacizumab, a well-established anti-VEGF monoclonal antibody used in specific cancer treatment protocols.

Its anti-angiogenic mechanism targets VEGF, a pathway involved in the development of blood vessels that support tumor growth.

The Roche-manufactured Avastin 100mg presentation provides a convenient vial strength that can be used as part of an individualized intravenous treatment dose.

Because Avastin is a specialized prescription oncology medicine, it should only be used under the supervision of an experienced oncologist.

Frequently Asked Questions About Avastin 100mg

What is Avastin 100mg Injection?

Avastin 100mg Injection is a prescription biological cancer medicine containing bevacizumab, an anti-VEGF monoclonal antibody used in selected cancer treatment regimens.

What is the generic name of Avastin?

The generic name of Avastin is bevacizumab.

Who manufactures Avastin 100mg Injection?

The manufacturer of the product listed here is Roche.

What is the pack size of Avastin 100mg?

The pack size for this product is 1 injection/vial.

How is Avastin 100mg administered?

Avastin 100mg is administered by intravenous infusion after appropriate dilution by a qualified healthcare professional.

How often is Avastin given?

The dosing interval depends on the cancer being treated and the combination regimen. Some treatment protocols use Avastin every two weeks, while others use an every-three-week schedule.

Is Avastin chemotherapy?

Avastin is not traditional chemotherapy. It is a targeted biological therapy and monoclonal antibody that inhibits VEGF. It may be administered together with chemotherapy.

What cancers can Avastin treat?

Bevacizumab is used in specific treatment regimens for selected colorectal, lung, kidney, brain and gynecological cancers. The exact indication depends on the patient’s diagnosis and applicable approved treatment protocol.

Does Avastin require medical supervision?

Yes. Avastin is an injectable prescription oncology medicine and must be prepared and administered under appropriate medical supervision.

Can Avastin 100mg be purchased without a prescription?

Avastin is a specialized prescription medicine and should only be used under the supervision of a qualified oncologist or healthcare professional.

Order Avastin 100mg Injection in Pakistan

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MedicineWalyDost.com provides access to specialized prescription medicines and oncology products. Contact us to check the latest Avastin 100mg price, availability and ordering information.

Before ordering, confirm the brand, strength, active ingredient, manufacturer, pack size and prescription requirements with your doctor or pharmacist.

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Important Medical Disclaimer

Avastin 100mg Injection is a prescription cancer medicine. This product description is intended for educational and e-commerce purposes only and does not replace professional medical advice. Avastin should be prescribed, prepared and administered by qualified healthcare professionals. Do not change the dose, treatment schedule or duration without medical advice.