Regocent XR 15mg Tablet (Upadacitinib) – Extended Release JAK Inhibitor for Autoimmune Diseases

What is Regocent XR 15mg Tablet?

Regocent XR 15mg is an extended-release oral tablet containing Upadacitinib, a selective Janus kinase (JAK) inhibitor. It is prescribed for adults with moderate to severe autoimmune and inflammatory conditions such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and atopic dermatitis. Designed for once-daily dosing, Regocent XR helps reduce inflammation by targeting key enzymes involved in immune system signaling.

How Does Regocent XR Work?

Upadacitinib, the active ingredient in Regocent XR, selectively blocks the JAK1 enzyme involved in cytokine signaling pathways that promote inflammation. By inhibiting JAK1, Regocent XR reduces the activity of pro-inflammatory molecules, helping to control symptoms such as joint pain, swelling, and skin inflammation. Its extended-release formulation ensures steady drug levels over 24 hours, improving patient convenience and treatment adherence.

Uses and Indications of Regocent XR 15mg

Regocent XR 15mg is approved for the treatment of several immune-mediated inflammatory diseases, including:

• Rheumatoid Arthritis: For patients with moderate to severe disease who have not responded well to other therapies.

• Psoriatic Arthritis: Effective in reducing joint inflammation and skin symptoms.

• Ulcerative Colitis: Used for induction and maintenance of remission in moderate to severe cases.

• Atopic Dermatitis: For patients aged 12 years and older when topical treatments are insufficient.

This medication can be used alone or in combination with other disease-modifying drugs depending on the patient’s condition.

How to Take Regocent XR 15mg Tablet

• Dosage: Take one 15mg tablet once daily, preferably at the same time each day.

• Administration: Swallow the tablet whole with water; do not crush, chew, or break the tablet to maintain its extended-release properties.

• Food: Regocent XR can be taken with or without food.

• Missed Dose: If you miss a dose, take it as soon as possible unless it’s close to the next dose; do not double up.

Always follow your healthcare provider’s instructions for dosing and duration.

Benefits of Regocent XR 15mg

• Targeted Treatment: Selective JAK1 inhibition offers effective symptom control with a potentially better safety profile than less selective JAK inhibitors.

• Convenient Dosing: Once-daily extended-release tablet improves compliance.

• Proven Effectiveness: Clinical studies show significant improvement in joint function, reduced skin lesions, and maintenance of disease remission.

• Rapid Onset: Many patients experience symptom relief within 2 weeks of starting treatment.

Possible Side Effects of Regocent XR

Common side effects include:

• Upper respiratory infections

• Nausea and headache

• Increased liver enzymes

• Cough and fever

Serious but less common risks:

• Increased risk of serious infections (e.g., tuberculosis, herpes zoster)

• Blood clots such as deep vein thrombosis or pulmonary embolism

• Possible increased risk of certain cancers

• Gastrointestinal perforations in patients with predisposing factors

If you experience symptoms like fever, persistent cough, chest pain, or unusual bruising, seek medical help immediately.

Precautions and Safety Information

• Screening: Prior to starting Regocent XR, patients should be tested for latent tuberculosis and viral infections.

• Monitoring: Regular blood tests to monitor liver function, blood cell counts, and lipid levels are important during treatment.

• Vaccinations: Avoid live vaccines while on Regocent XR.

• Pregnancy: Not recommended during pregnancy or breastfeeding; effective contraception is advised during treatment.

• Drug Interactions: Inform your doctor about all medications you take, especially CYP3A4 inhibitors or inducers, as they may affect Regocent XR levels.

Storage Instructions for Regocent XR 15mg

Store Regocent XR tablets at room temperature (below 25°C), away from moisture and direct sunlight. Keep the medication in its original packaging and out of reach of children.

Why Choose Regocent XR 15mg?

Regocent XR offers a modern, effective option for managing chronic autoimmune diseases with a convenient once-daily tablet that fits easily into your lifestyle. Its selective action on the JAK1 enzyme helps reduce inflammation and improve quality of life with a manageable safety profile.

Consult Your Doctor

Always consult a healthcare professional before starting or stopping Regocent XR 15mg. Proper medical supervision ensures the best outcomes and helps manage potential risks effectively.

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