Soranib Tablets 200 mg (Sorafenib) – Uses, Price in Pakistan, Dosage & Side Effects

Buy Soranib 200 mg Tablets (Sorafenib) at the best price in Pakistan from MedicineWalyDost.com. This imported oncology medicine, widely known under the brand name Nexavar, is a powerful multikinase inhibitor used to treat advanced cancers of the liver (hepatocellular carcinoma), kidney (renal cell carcinoma), and radioiodine‑refractory thyroid cancer

What Is Soranib 200 mg Tablet Used For?

• Advanced renal cell carcinoma (kidney cancer) after failure of previous therapy

• Unresectable hepatocellular carcinoma (HCC) when surgery isn’t an option

• Differentiated thyroid carcinoma (radioiodine-resistant) that has metastasized or progressed

Occasionally used off-label or in clinical trials for aggressive tumors such as desmoid tumors 

How Does Sorafenib Work?

Sorafenib is a protein kinase inhibitor that blocks key proteins (VEGFR, PDGFR, RAF) essential for tumor growth and angiogenesis. It works by halting cancer cell proliferation and cutting off blood supply to tumors. Its anti-angiogenic, anti-proliferative, and pro‑autophagy properties make it an effective targeted cancer therapy.

Soranib Tablet Price in Pakistan

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Dosage & Administration

• Strength: 200 mg film‑coated tablet

• Typical Dose: 400 mg orally twice daily (total 800 mg/day) on an empty stomach—take at least 1 hour before or 2 hours after meals.

• Duration: Continue daily until disease progression or intolerance.

• Dose Adjustments: Based on tolerability or side effects under oncologist’s guidance.

Common Side Effects of Sorafenib

Side effects occur frequently and may impact treatment adherence:

• Hand-foot skin reaction (HFS) or rash, hair thinning or alopecia, diarrhea, fatigue, weight loss, loss of appetite, and hypertension 

• Others include: nausea, pain, pruritus, arthralgia, mild bleeding or hypophosphatemia

Serious But Rare Side Effects

Patients should be aware of potentially severe but uncommon reactions:

• Severe bleeding events (e.g., gastrointestinal, intracranial)

• Heart-related issues: chest pain, heart attack, QT prolongation, arrhythmias 

• Liver toxicity, jaundice, acute liver failure 

• Gastrointestinal perforation, hypertension crisis, severe skin reactions (e.g. Stevens–Johnson syndrome)

Warnings, Precautions & Drug Interactions

• Not recommended with carboplatin + paclitaxel in squamous cell lung cancer due to increased risk

• Contraindicated or used with caution in patients with heart disease, hypertension, bleeding disorders, liver or kidney impairment, or recent surgery

• Avoid with CYP3A4 inducers or inhibitors (e.g., rifampicin, ketoconazole) and warfarin, as interactions may alter blood levels or bleeding risk

• Do not consume grapefruit or starfruit juice; avoid high-fat meals around dosing time 

Monitoring & Follow‑Up

Regular assessments improve safety and outcomes:

• Blood pressure: monitor weekly or as prescribed

• Liver function tests and renal panel periodically

• CBC tests to check platelets, hemoglobin, and white cell count

• Monitor skin changes, bleeding signs, and thyroid function as needed

Storage Guidelines

• Store at 20–25 °C, away from moisture and direct sunlight

• Do not freeze

• Keep tablets in original sealed container

• Keep out of reach of children 

Manufacturer & Authenticity

• Brand Name: Soranib (Cipla)

• Generic Name: Sorafenib

• Form: 200 mg film-coated tablet

• Manufacturer: Cipla Pharma

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• Best Soranib 200 mg price in Pakistan

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Order Soranib 200 mg Online in Pakistan

Soranib 200 mg (Sorafenib) is an essential oral targeted cancer therapy for advanced kidney, liver, and thyroid cancers. With its multikinase inhibition and anti-angiogenic action, it offers proven benefits in progression-free survival.

Need to buy Soranib 200 mg tablets online in Pakistan? Visit MedicineWalyDost.com today to order original Sorafenib with secure nationwide delivery and expert support.

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