Imfinzi 500mg Injection (Durvalumab)

Imfinzi 500mg Injection contains durvalumab, a monoclonal antibody and programmed death-ligand 1 (PD-L1) immune checkpoint inhibitor used in the treatment of several types of cancer. It is manufactured by AstraZeneca and supplied as a single-dose 500mg/10mL vial for intravenous (IV) infusion after dilution. Official product information identifies the 500mg presentation as a single-dose vial containing 50mg/mL durvalumab.

Durvalumab works by blocking the interaction between PD-L1 and its receptors, helping restore the ability of the immune system to recognize and attack cancer cells. Imfinzi is a prescription oncology medicine and should only be administered under the supervision of a qualified oncologist or healthcare professional.

Imfinzi 500mg Injection Uses

Imfinzi (durvalumab) may be prescribed for specific cancer indications depending on the patient’s diagnosis, disease stage, biomarker status, previous treatment and applicable treatment protocol. Current prescribing information includes indications involving cancers such as:

• Non-small cell lung cancer (NSCLC)
• Small cell lung cancer (SCLC)
• Biliary tract cancer (BTC)
• Hepatocellular carcinoma (HCC)
• Endometrial cancer
• Certain bladder/urothelial cancers
• Certain gastric or gastroesophageal junction cancers

The exact indication and whether Imfinzi is used alone or with other anticancer medicines depends on the approved treatment regimen and the patient’s individual clinical circumstances.

How Does Imfinzi 500mg Work?

The active ingredient, durvalumab, is a human monoclonal antibody that targets PD-L1. Some cancer cells use the PD-1/PD-L1 pathway to reduce immune-system activity and avoid being attacked.

By binding to PD-L1, durvalumab blocks this immune-suppressing signal. This can help T cells recognize and respond against cancer cells. Because Imfinzi modifies immune-system activity, it can also cause immune-mediated reactions affecting healthy tissues, which is why careful medical monitoring is important.

Imfinzi 500mg Injection Strength & Pack Size

Product Information	Details
Brand Name	Imfinzi
Active Ingredient	Durvalumab
Strength	500mg/10mL
Concentration	50mg/mL
Dosage Form	Injection / concentrate for IV infusion
Route	Intravenous infusion after dilution
Pack Size	1 injection / 1 single-dose vial
Manufacturer	AstraZeneca
Storage	2°C to 8°C; do not freeze or shake

The 500mg presentation contains 10mL of durvalumab concentrate in a single-dose vial. It is preservative-free and intended for dilution before intravenous administration.

Imfinzi 500mg Dosage

The appropriate dose of Imfinzi depends on the cancer being treated and whether it is being administered as monotherapy or in combination with other anticancer treatments. Some treatment protocols use weight-based dosing, while other approved regimens use fixed dosing at specified intervals.

Imfinzi should not be self-administered. A qualified oncologist determines the appropriate dose, infusion schedule and duration of treatment based on the approved regimen and the patient’s medical condition.

Dose adjustments, treatment delays or discontinuation may be necessary if serious immune-mediated or infusion-related adverse reactions occur.

How Is Imfinzi 500mg Administered?

Imfinzi 500mg is administered through an intravenous infusion after appropriate dilution. The vial is intended for single use and unused medicine should be discarded.

Healthcare professionals should inspect the solution before preparation. The product should not be shaken, and the concentrate must be diluted according to the official preparation and administration instructions.

Common Side Effects of Imfinzi

Like other immunotherapy medicines, Imfinzi can cause side effects. Common adverse reactions may vary according to the cancer type and combination therapy used.

Possible side effects include:

• Fatigue or weakness
• Diarrhea
• Nausea
• Decreased appetite
• Rash or itching
• Cough
• Shortness of breath
• Abdominal discomfort
• Constipation
• Fever
• Musculoskeletal pain

Patients receiving Imfinzi in combination with chemotherapy may experience additional treatment-related adverse effects.

Serious Side Effects and Immune-Mediated Reactions

Because durvalumab activates the immune system, it can cause immune-mediated adverse reactions. These reactions can affect different organs and, in some cases, can become severe or life-threatening.

Important reactions can include:

• Pneumonitis or inflammation of the lungs
• Colitis or severe intestinal inflammation
• Hepatitis or liver inflammation
• Endocrine disorders involving the thyroid, adrenal or pituitary glands
• Nephritis and kidney dysfunction
• Pancreatitis
• Severe skin reactions
• Infusion-related reactions
• Other immune-mediated complications

Patients should promptly inform their healthcare provider about new or worsening symptoms during treatment. Monitoring of liver enzymes, kidney function and thyroid function may be required during therapy.

Precautions Before Using Imfinzi

Before receiving Imfinzi 500mg Injection, patients should tell their doctor about all existing medical conditions and medicines they are taking. Particular attention may be required for patients with:

• Previous immune-system disorders
• Lung or breathing problems
• Liver problems
• Kidney problems
• Thyroid or other endocrine disorders
• Previous organ transplantation
• Previous severe reactions to immunotherapy
• Pregnancy or plans to become pregnant

Patients should also inform their healthcare team about all prescription medicines, over-the-counter medicines, vitamins and supplements they use.

Imfinzi During Pregnancy and Breastfeeding

Durvalumab may cause fetal harm because it affects immune-system pathways. Women who may become pregnant should discuss appropriate contraception and pregnancy-related precautions with their healthcare provider before and during treatment.

Breastfeeding is generally not recommended during treatment with Imfinzi and for the period advised by the treating healthcare professional.

Storage of Imfinzi 500mg Injection

Imfinzi 500mg injection should be stored according to the manufacturer’s requirements. The product should generally be kept refrigerated at 2°C to 8°C, protected from light and kept in its original carton. Do not freeze or shake the vial.

Proper cold-chain handling is particularly important when purchasing or transporting biological medicines such as durvalumab.

Imfinzi 500mg Injection Price in Pakistan

The price of Imfinzi 500mg Injection in Pakistan can vary depending on availability, importer/distributor, batch, exchange rates, supply conditions and applicable pharmacy charges. For the current Imfinzi 500mg price in Pakistan, customers should confirm the latest price and availability before ordering.

Why Buy Imfinzi 500mg from MedicineWalyDost.com?

MedicineWalyDost.com provides access to a range of prescription and specialty medicines for customers looking for genuine pharmaceutical products. Imfinzi is a specialist oncology medicine and should be sourced through a reliable pharmaceutical supplier with appropriate handling and storage.

Before purchasing, customers should verify the required strength, prescription and treatment plan with their oncologist.

Frequently Asked Questions

What is Imfinzi 500mg Injection?

Imfinzi 500mg Injection is an intravenous cancer immunotherapy containing durvalumab, a PD-L1 blocking monoclonal antibody.

What is the generic name of Imfinzi?

The generic name is durvalumab.

Who manufactures Imfinzi 500mg?

Imfinzi is manufactured by AstraZeneca. Official product information identifies AstraZeneca as the manufacturer/labeler for the product.

How many vials are in an Imfinzi 500mg pack?

The specified pack size is 1 injection, supplied as one single-dose 500mg/10mL vial.

Is Imfinzi 500mg a chemotherapy medicine?

Imfinzi is immunotherapy, not conventional cytotoxic chemotherapy. It is a PD-L1 immune checkpoint inhibitor and may be used alone or together with chemotherapy or other anticancer treatments depending on the approved indication.

Can Imfinzi 500mg be self-injected?

No. Imfinzi is an intravenous infusion medicine that must be prepared and administered by qualified healthcare professionals.

Does Imfinzi have serious side effects?

Yes. Immune-mediated reactions can affect organs including the lungs, liver, kidneys, intestines, skin and endocrine system. Prompt medical assessment is important if concerning symptoms develop.

Order Imfinzi 500mg Injection Online in Pakistan

If your oncologist has prescribed Imfinzi 500mg Injection (Durvalumab), you can contact MedicineWalyDost.com to check the latest availability and price. Always use Imfinzi under specialist medical supervision and follow your oncologist’s prescribed treatment schedule.

Order Imfinzi 500mg Injection from MedicineWalyDost.com today and confirm current availability, pricing and delivery options before placing your order.

Product Summary

Imfinzi 500mg Injection (Durvalumab) is a prescription PD-L1 immune checkpoint inhibitor manufactured by AstraZeneca. Each pack contains 1 single-dose 500mg/10mL vial intended for intravenous infusion after dilution. It is used in specific oncology treatment protocols for several cancers, with treatment selection and dosing determined by a qualified oncologist.