Ofev 150mg Capsule (Nintedanib) – Long Product Description

Ofev 150mg Capsule (Nintedanib) is a prescription antifibrotic medicine containing 150mg of nintedanib. It is manufactured by Boehringer Ingelheim and is supplied in a pack size of 60 capsules. Ofev is primarily used in adults with idiopathic pulmonary fibrosis (IPF) and certain other chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype. It is also indicated to slow the decline in lung function associated with systemic sclerosis-associated interstitial lung disease (SSc-ILD). 

Ofev 150mg Capsule – Product Information

• Brand Name: Ofev
• Active Ingredient: Nintedanib
• Strength: 150mg
• Dosage Form: Soft Capsule
• Manufacturer: Boehringer Ingelheim
• Pack Size: 60 Capsules
• Route of Administration: Oral
• Prescription Status: Prescription medicine
• Therapeutic Category: Antifibrotic / Kinase Inhibitor

The 150mg Ofev capsule is described as a brown, opaque, oblong soft capsule marked with the Boehringer Ingelheim symbol and “150.” The 150mg presentation is supplied in bottles containing 60 capsules. 

What Is Ofev 150mg Used For?

Ofev 150mg contains nintedanib, a kinase inhibitor that helps interfere with signaling pathways involved in abnormal tissue growth and fibrosis. It is used under specialist medical supervision for several progressive fibrotic lung conditions.

Ofev may be prescribed for:

• Idiopathic pulmonary fibrosis (IPF)
• Chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype
• Systemic sclerosis-associated interstitial lung disease (SSc-ILD)

The treatment is intended to help slow the rate of decline in pulmonary function rather than provide an immediate cure for pulmonary fibrosis. 

How Does Nintedanib Work?

Nintedanib is a tyrosine kinase inhibitor with antifibrotic activity. It targets signaling pathways associated with growth factors involved in fibrotic processes. By inhibiting these pathways, nintedanib can help reduce the progression of abnormal fibrotic changes in the lungs.

Because pulmonary fibrosis can progressively impair lung function, treatment with Ofev is generally aimed at slowing disease progression and preserving lung function for as long as possible.

Ofev 150mg Dosage and Administration

For adults with the approved pulmonary fibrosis indications, the commonly recommended dose is 150mg twice daily, approximately 12 hours apart, and the capsules should be taken with food. 

Ofev capsules should be swallowed whole with liquid. Do not chew, crush, or open the capsules. If a dose is missed, the next dose should be taken at the scheduled time rather than taking an extra dose to compensate. 

Your doctor may reduce the dose to 100mg twice daily or temporarily interrupt treatment if side effects occur or if the full 150mg dose is not tolerated. Dose adjustments should only be made under medical supervision.

Common Side Effects of Ofev 150mg

Like all prescription medicines, Ofev can cause side effects. Commonly reported adverse effects include:

• Diarrhea
• Nausea
• Abdominal pain
• Vomiting
• Reduced appetite
• Weight loss
• Increased liver enzymes
• Headache

Diarrhea is particularly common with nintedanib treatment and should be discussed with a healthcare professional if it is persistent or severe.

Ofev may also cause liver enzyme elevations and drug-induced liver injury, so healthcare professionals may recommend periodic liver function testing during treatment. 

Important Precautions

Ofev 150mg should be used only according to the prescribing physician’s instructions. Tell your doctor if you have:

• Liver disease or abnormal liver function
• A history of bleeding problems
• A tendency to develop blood clots
• Cardiovascular disease
• A history of gastrointestinal problems
• Recent or planned surgery
• A known allergy to nintedanib or any ingredient in the medicine

Ofev is not recommended for patients with moderate or severe hepatic impairment (Child-Pugh B or C). Patients with mild hepatic impairment may require a reduced dose. 

Pregnancy and Breastfeeding

Nintedanib can cause fetal harm. Women who can become pregnant should discuss pregnancy prevention with their healthcare professional before starting treatment. The current prescribing information advises effective contraception during treatment and for at least 3 months after stopping Ofev. 

Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not start or stop treatment without medical advice.

Ofev 150mg Contraindications

The official U.S. prescribing information does not list a specific absolute contraindication, but Ofev should not be taken by individuals with a known serious hypersensitivity to nintedanib or its ingredients. 

Patients with significant liver impairment require particular caution, and Ofev is not recommended in moderate or severe hepatic impairment. 

Storage of Ofev 150mg Capsules

Store Ofev at room temperature, generally 20°C to 25°C, with permitted excursions between 15°C and 30°C. Protect the capsules from excessive heat and high humidity and keep the medicine out of the reach of children. 

Ofev 150mg Pack Size

Ofev 150mg Capsule – 60 Capsules

The 150mg presentation is officially supplied as a 60-capsule bottle. 

Ofev 150mg Manufacturer

Manufacturer: Boehringer Ingelheim

Boehringer Ingelheim is the pharmaceutical company associated with the Ofev brand. Product manufacturing and packaging arrangements can vary by market, so buyers should check the packaging and product information supplied with their specific product.

Ofev 150mg Price in Pakistan

The price of Ofev 150mg in Pakistan can vary depending on availability, import status, supplier, exchange rates, and pharmacy pricing. For the latest Ofev 150mg price and availability, customers can contact MedicineWalyDost.com before ordering.

Why Buy Ofev 150mg from MedicineWalyDost.com?

If you are looking for Ofev 150mg Capsules in Pakistan, MedicineWalyDost.com can help you check product availability and ordering information. Because Ofev is a prescription medicine used for serious chronic lung conditions, it should be purchased and used under appropriate medical supervision.

Order Ofev 150mg Capsule (Nintedanib) from MedicineWalyDost.com and contact us to confirm current availability, pricing, and delivery options in Pakistan.

Frequently Asked Questions About Ofev 150mg

What is Ofev 150mg?

Ofev 150mg is a prescription medicine containing nintedanib. It is an antifibrotic kinase inhibitor used for adults with idiopathic pulmonary fibrosis, progressive fibrosing interstitial lung disease, and systemic sclerosis-associated interstitial lung disease.

How many Ofev 150mg capsules are in one pack?

The specified pack contains 60 capsules.

Who manufactures Ofev 150mg?

Ofev is manufactured/marketed by Boehringer Ingelheim.

How often is Ofev 150mg taken?

For the approved pulmonary fibrosis indications, the recommended adult dose is generally 150mg twice daily, approximately 12 hours apart, with food. Always follow your physician’s specific instructions. 

Can Ofev 150mg cure pulmonary fibrosis?

Ofev is not considered a cure for pulmonary fibrosis. Its purpose is to help slow the decline in lung function and disease progression in its approved indications.

What is the most common side effect of Ofev?

Diarrhea is one of the most commonly reported side effects. Persistent or severe diarrhea should be discussed with a healthcare professional.

Does Ofev require liver monitoring?

Yes. Ofev can cause elevated liver enzymes and, in some cases, liver injury. Healthcare professionals may perform liver function tests before and during treatment. 

Is Ofev available without a prescription?

Ofev is a prescription medicine and should be used under the supervision of a qualified healthcare professional.

Key Product Summary

Ofev 150mg Capsule (Nintedanib) is an antifibrotic prescription treatment manufactured by Boehringer Ingelheim and supplied in a 60-capsule pack. It is used in adults with approved fibrosing lung conditions, including idiopathic pulmonary fibrosis, progressive fibrosing ILD, and systemic sclerosis-associated ILD. The usual adult dose for these indications is 150mg twice daily with food, although dose modification may be required depending on tolerability and individual patient factors. 

Important: This product description is for general informational and SEO purposes and does not replace professional medical advice. Ofev should be taken only as prescribed by a qualified healthcare professional.