Dostinex (Caborgolin 0.5mg) Tablet – Product Description

What is Dostinex Used For?
Dostinex (Cabergoline) is a dopamine agonist prescribed to lower elevated levels of prolactin, a hormone produced by the pituitary gland. This condition, known as hyperprolactinemia, can lead to irregular menstrual cycles, infertility, or unwanted milk production in non-breastfeeding women. Dostinex is also prescribed to inhibit milk production in women who need to avoid breastfeeding for medical reasons.

Dosage and Administration
Initial Dose:

The typical starting dose for Dostinex is 0.25 mg twice a week.
Adjustment of Dose:

Dosage can be gradually increased by 0.25 mg twice weekly based on serum prolactin levels.
The maximum recommended dose is 1 mg twice a week.
Dose adjustments should occur no more frequently than every four weeks to allow monitoring of the patient’s response.
Maintenance Therapy:

After six months of maintaining normal prolactin levels, treatment may be discontinued. Regular monitoring of serum prolactin is advised to determine if therapy should be resumed.
Important Considerations:

Cardiovascular assessment, including echocardiography, may be required before starting treatment to evaluate heart valve function.
Patients receiving long-term therapy should undergo periodic cardiac evaluations.
Important Warnings
Heart Valve Issues:
Dostinex may cause heart valve abnormalities. Your doctor will monitor heart function before and during treatment using echocardiograms and other tests. Avoid Dostinex if you have pre-existing heart valve conditions.
Fibrosis Risk:
Dostinex can cause scarring of tissues in the lungs, heart, or abdomen (fibrosis). Symptoms include:
Persistent cough
Difficulty breathing
Chest or abdominal pain
Swelling of legs and feet
Inform your doctor immediately if you experience these symptoms.
Pregnancy and Breastfeeding:
Consult your doctor before using Dostinex if you are pregnant, planning to become pregnant, or breastfeeding.
Precautions
Inform your doctor if you are allergic to Cabergoline or any ergot medications (e.g., ergotamine).
Disclose any history of heart disease, lung disease, or fibrosis.
Regular monitoring of prolactin levels and cardiovascular health is recommended during treatment.
Storage
Store at room temperature, between 20°C to 25°C (68°F to 77°F).
Keep the tablets in their original packaging to protect them from light and moisture.
How Dostinex Works
Dostinex (Cabergoline) reduces prolactin levels by stimulating dopamine receptors in the brain. This action suppresses prolactin secretion from the pituitary gland, helping to restore hormonal balance and resolve symptoms associated with hyperprolactinemia.

Uses
Hyperprolactinemia Treatment:
Effective in reducing elevated prolactin levels caused by pituitary gland disorders.
Menstrual Irregularities and Infertility:
Helps regulate menstrual cycles and improve fertility in women.
Milk Suppression:
Prevents unwanted milk production in non-breastfeeding women for medical reasons.
Side Effects
Common Side Effects:

Nausea
Vomiting
Dizziness
Fatigue
Abdominal pain
Constipation
Serious Side Effects:

Persistent coughing or difficulty breathing
Swelling in legs or feet
Chest pain
Symptoms of heart valve issues or fibrosis
If you experience serious side effects, seek medical attention immediately.

Tags & Categories
Categories:

Endocrinology
Reproductive Medicine
Hormonal Therapy
Prescription Medications
Tags:

Cabergoline
Dostinex price in Pakistan
Hormonal balance
Fertility treatment
Prolactin suppression
Hyperprolactinemia
Dopamine agonist
Reproductive health
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